Transgenic animal expressing a familial form of human...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/10 (2006.01) A01K 67/027 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2198451

Transgenic mice with a gene encoding human amyloid precursor protein gene are provided. The transgenic mice may be used to evaluate compounds affecting Alzheimer's Disease and other cognitive disorders.

Cette invention se rapporte à des souris transgéniques ayant un gène codant des gènes de protéines précurseurs de l'amyloïde humaine. Ces souris transgéniques peuvent être utilisées pour évaluer des composés modifiant le développement de la maladie d'Alzheimer et d'autres troubles de la connaissance.

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