Transgenic animal model

Details Transgenic animal model Transgenic animal model

A - Human Necessities

01

K

A01K 67/027 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2672509

The present invention is related to a transgenic, non-human animal, particularly a transgenic rodent, but especiaily a transgenic mouse model which allows for the simultaneous, tissue-specific and temporally-controlled regulation of transgene expression and can be used as a tool to investigate the consecutive steps involved in initiation and progression of certain diseases such as cancer, but particularly lung cancer.

La présente invention porte sur un modèle d'animal non humain, transgénique, en particulier sur un modèle de rongeur transgénique, mais notamment sur un modèle de souris transgénique qui permet la régulation simultanée, spécifique du tissu et contrôlée dans le temps de l'expression d'un transgène et qui peut être utilisé comme outil pour rechercher les étapes consécutives mises en jeu dans l'initiation et la progression de certaines maladies telles que le cancer, mais en particulier le cancer du poumon.

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