Transgenic animals and uses thereof

Details Transgenic animals and uses thereof Transgenic animals and uses thereof

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) A01K 67/027 (2006.01) C07K 16/00 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2563064

In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and method of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.

D'une manière générale, la présente invention a trait à des mammifères non humains génétiquement modifiés (par exemple, des bovins et autres ongulés), et un procédé pour la production de ces animaux. En particulier, l'invention a trait à des ongulés transgéniques présentant des niveaux réduits de chaîne d'IgM endogène et/ou de protéine prion.

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