A - Human Necessities – 01 – K
Patent
A - Human Necessities
01
K
A01K 67/027 (2006.01) C07K 14/34 (2006.01) C12N 15/85 (2006.01) G01N 33/15 (2006.01) G01N 33/48 (2006.01)
Patent
CA 2147933
Transgenic animals (e.g., rat, mouse) carrying a chimeric gene coding diphtheria toxin A chain transduced at a downstream site of the promoter of an osteocalcin gene. The transgenic animals can be used as a model for metabolic bone diseases since they have decreased bone mass associated with a marked reduction in the number of osteoblasts.
Hirokawa Katsuiku
Ikeda Toru
Kobayashi Takashi
Sato Masahiro
Tada Norihiro
Bereskin & Parr
Hoechst Japan Limted
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