Transgenic animals for testing multidrug resistance

C - Chemistry – Metallurgy – 12 – N

Patent

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167/46, 195/1.36

C12N 5/10 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2001128

ABSTRACT OF THE DISCLOSURE Transgenic animals carrying and expressing human MDR1 gene have been produced. These transgenic animals serve as a useful model for testing the efficacy of high dosage chemotherapy and for the development of novel chemotherapeutic agents against cancers.

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