Transgenic animals harboring app allele having swedish mutation

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2174429

The invention provides transgenic non-human animals and transgenic non-human mammalian cells harboring a transgene encoding an APP polypeptide comprising the Swedish mutation.

Cette invention concerne des animaux transgéniques non humains et des cellules de mammifères transgéniques non humains hébergeant un transgène qui code un polypeptide APP comprenant la mutation suédoise.

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