Transgenic mammals

Details Transgenic mammals Transgenic mammals

A - Human Necessities

01

K

A01K 67/027 (2006.01) C07K 14/705 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2297105

Transgenic non-human mammals which have a human complement regulator (DAF/CD55) gene and in which this regulator has been expressed in the organs and tissues, in particular, vascular endothelial cells. These transgenic mammals are useful as laboratory animals in the fields of medicine, pharmacy, etc. and/or sources for organs, tissues, cells, etc. to be used in treating humans.

L'invention concerne des mammifères transgéniques non humains présentant un gène régulateur du complément humain (DAF/CD55) et dans lesquels ce régulateur a été exprimé dans les organes et les tissus, notamment les cellules endothéliales vasculaires. Ces mammifères transgéniques sont utiles comme animaux de laboratoire dans les domaines de la médecine, de la pharmacie, etc. et/ou comme sources d'organes, de tissus, de cellules, etc. à utiliser dans le traitement de patients humains.

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