Transgenic mice containing targeted gene disruptions

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 14/72 (2006.01) C12N 9/10 (2006.01) C12N 9/16 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2402912

The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in genes, which are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.

La présente invention concerne des animaux transgéniques ainsi que des compositions et des procédés concernant la caractérisation de la fonction du gène. De manière spécifique, la présence invention traite de souris transgéniques présentant des interruptions de gènes, qui présentent une grande utilité comme modèles pour des maladies et permettent d'identifier des agents qui modulent l'expression et la fonction du gène. En outre, l'invention traite de traitements potentiels de diverses maladies et conditions.

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