C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) A01K 67/027 (2006.01) C07K 14/16 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2204572
The present invention relates to a transgenic mouse to serve as a small animal model of AIDS which comprises the entire HIV-1 coding sequences under the control of the human CD4 gene promoter flanked by the enhancer of the mouse CD4 gene for expression in T cells. There is also provided a method to screen for therapeutic agents for the treatment of AIDS, which comprises the steps of: a) administering the therapeutic agent to the mouse of the present invention; and b) determining the effects of the therapeutic agent.
Utilisation d'une souris transgénique comme petit modèle animal du SIDA, comprenant l'ensemble des séquences codantes du VIH-1 sous la commande du promoteur du gène humain CD4 flanqué par l'activateur du gène CD4 de la souris, à exprimer dans les cellules T. Une méthode de sélection d'agents thérapeutiques destinés au traitement du SIDA est également présentée. Elle comprend les étapes suivantes : a) administrer l'agent thérapeutique à la souris de la présente invention; et b) déterminer les effets de l'agent thérapeutique.
Jolicoeur Paul
Kay Denis G.
Zaher Hanna
Jolicoeur Paul
Kay Denis G.
Swabey Ogilvy Renault
Zaher Hanna
LandOfFree
Transgenic mice expressing hiv-1 in immune cells and uses... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Transgenic mice expressing hiv-1 in immune cells and uses..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transgenic mice expressing hiv-1 in immune cells and uses... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1778409