Transgenic non-human animal carrying a non-infectious hiv...

Details Transgenic non-human animal carrying a non-infectious hiv... Transgenic non-human animal carrying a non-infectious hiv...

C - Chemistry, Metallurgy

12

N

C12N 15/49 (2006.01) A01K 67/027 (2006.01) C07K 14/16 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/87 (2006.01) C12Q 1/37 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2042625

13-BG-D-36 Transqenic Non-Human Animal Carrying A Non- infectious HIV Genome Abstract of the Disclosure Disclosed herein is a transgenic non-human animal carrying a transgene which expresses non- infectious HIV-1 ribonucleic acid and complementary proteins thereof. Among the expressed proteins, which can be found in the milk, serum and several tissues, are the gag and envelope proteins. The transgenic animal is useful as a source for obtaining the complementary proteins, and as an animal model to study HIV host cell interactions and to evaluate anti-HIV drugs.

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