Transgenic non-human animal model for developing and testing...

Details Transgenic non-human animal model for developing and testing... Transgenic non-human animal model for developing and testing...

G - Physics

01

N

G01N 33/564 (2006.01) A01K 67/027 (2006.01) C07K 14/705 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2116012

2116012 9304168 PCTABS00020 A method is provided for developing therapies to effectively treat sepsis and for studying the cellular and molecular mechanisms that result in sepsis, using an in vivo system comprised of transgenic non-human animal whose germ cells and somatic cells contain and express the human gene for the CD14 myelomonocytic differenctiation marker. The gene is introduced into an embryo of the non-human animal or of an ancestor of the non-human animal. The resulting non-human animal is characterized by a heightened sensitivity toward endotoxin-induced sepsis that is mediated by the gene product of the human CD14 gene.

Affiliated with

Also associated with

Rating

Transgenic non-human animal model for developing and testing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transgenic non-human animal model for developing and testing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transgenic non-human animal model for developing and testing... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1832629