C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/82 (2006.01) A01H 5/00 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01)
Patent
CA 2253454
The present invention relates to expression and assembly of foreign multimeric proteins - e.g., antibodies - in plants, as well as to transgenic plants that express such proteins. In one of several preferred embodiments, the generation and assembly of functional secretory antibodies in plants is disclosed. The invention also discloses compositions produced by the transgenic plants of the present invention and methods of using same.
La présente invention concerne l'expression et l'assemblage de protéines multimères étrangères telles que des anticorps dans des plantes. L'invention concerne également des plantes transgéniques exprimant de telles protéines. L'invention concerne en outre, selon l'une de ses différentes réalisations préférées, la génération et l'assemblage d'anticorps sécrétoires fonctionnels dans des plantes. L'invention concerne enfin, non seulement des compositions produites par les plantes transgéniques de la présente invention, mais aussi les procédés d'utilisation correspondants.
Hein Mich B.
Hiatt Andrew
Ma Julian K. C.
Smart & Biggar
The Scripps Research Institute
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