C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/82 (2006.01) A01H 5/00 (2006.01) A61K 38/00 (2006.01) C07K 14/47 (2006.01) C12N 9/10 (2006.01) C12N 9/90 (2006.01) C12N 15/54 (2006.01) C12N 15/61 (2006.01)
Patent
CA 2453574
The present invention relates to the use of transgenic plants for the expression of vitamin B12 (cobalamin) binding proteins. Plant cells are transformed with nucleotide sequences adapted for expression and secretion of vitamin B12 binding proteins. The present invention also relates to the use of recombinant vitamin B12 binding proteins from plants in analytical tests and treatment of vitamin B12 deficiency. Also disclosed is a method for purification of recombinant vitamin B12 binding proteins.
La présente invention concerne l'utilisation de plantes transgéniques pour l'expression de protéines de liaison à la vitamine B12 (cobalamine). Les cellules végétales sont transformées avec des séquences nucléotidiques destinées à l'expression et la sécrétion de protéines de liaison à la vitamine B12. La présente invention concerne également l'utilisation de protéines de liaison à la vitamine B12 issues de plantes dans des essais analytiques et dans le traitement d'une carence en vitamine B12. L'invention se rapporte en outre à une méthode de purification de protéines recombinantes de liaison à la vitamine B12.
Berglund Lars Erik
Fedosov Sergey Nikolaevich
Jensen Erik Ostergaard
Laursen Niels Bech
Nexo Ebba
Cobento A/s
Cobento Biotech Aps
Deeth Williams Wall Llp
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