Transgenically produced antithrombin iii

Details Transgenically produced antithrombin iii Transgenically produced antithrombin iii

C - Chemistry, Metallurgy

07

K

C07K 14/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2197675

This invention relates to transgenically produced human Antithrombin III (tgATIII). The human ATIII produced by the transgenic process of the present invention has a monosaccharide composition which comprises N-acetylgalactosamine (GalNAc) along with fucose, N-acetylglucosamine, galactose, mannose, and N-acetylneuraminic acid/N-glycolyneuraminic acid. The monosaccharide composition differs with that of plasma derived ATIII (phATIII). It has been found that tgATIII has an increased clearance rate when compared to phATIII.

L'invention concerne l'antithrombine III humaine produite par voie transgénique (tgATIII). L'ATIII humaine produite par le procédé transgénique de la présente invention présente une composition monosaccharidique comprenant une N-acétylgalactosamine (GalNAc) ainsi que du fucose, une N- acétylglucosamine, du galactose, du mannose, et de l'acide N- acétylneuraminique/acide N-glycolyneuraminique. La composition monosaccharidique diffère de celle du plasma dérivé de ATIII (phATIII). On a découvert que tgATIII présente un coefficient d'épuration accru comparé à phATIII.

Affiliated with

Also associated with

Rating

Transgenically produced antithrombin iii does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transgenically produced antithrombin iii, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transgenically produced antithrombin iii will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1818663