C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 327/56 (2006.01) A61K 31/166 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2741189
The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thiohydrazide amide] is represented by Structural Formula (I):, or a prodrug, isomer, ester, salt, hydrate, solvate, polymorph or a deprotonated form thereof. In one embodiment, the compound is represented by Structural Formula (II):, or a prodrug, isomer, ester, salt, hydrate, solvate or polymorph thereof. The present invention also provides a pharmaceutical composition comprising the compound of the invention and method of use thereof.
La présente invention concerne un composé comprenant un bis[amide de thiohydrazide] ou une forme déprotonée de celui-ci, complexé à un cation métallique de transition, le bis[amide de thiohydrazide] étant représenté par la formule développée (I) : , ou un promédicament, isomère, ester, sel, hydrate, solvate, forme polymorphe ou déprotonée de celui-ci. Dans un mode de réalisation, le composé est représenté par la formule développée (II) : , ou un promédicament, isomère, ester, sel, hydrate, solvate ou forme polymorphe de celui-ci. La présente invention concerne également une composition pharmaceutique comprenant le composé de linvention et un procédé pour son utilisation.
Nagai Masazumi
Shen Jianhua
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
LandOfFree
Transition metal complexes of bis[thiohydrazide amide]... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Transition metal complexes of bis[thiohydrazide amide]..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transition metal complexes of bis[thiohydrazide amide]... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2055168