Transmembrane serine protease overexpressed in ovarian...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/03 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2362830

The present invention provides a TADG-12 protein and a DNA fragment encoding such protein. Also provided is a vector/host cell capable of expressing the DNA. The present invention further provided various methods of early detection of associated ovarian and other malignancies, and of interactive therapies for cancer treatment by utilizing the DNA and/or protein disclosed herein.

La présente invention concerne une protéine TADG-12 et un fragment d'ADN codant pour une telle protéine. L'invention concerne également un vecteur/hôte pouvant exprimer l'ADN. L'invention concerne, en outre, divers procédés pour le dépistage précoce des malignités ovariennes et d'autres affections associées, et des thérapies interactives pour le traitement du cancer mettant en oeuvre l'ADN et/ou la protéine selon l'invention.

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