Transmucosal delivery of cannabinoids

Details Transmucosal delivery of cannabinoids Transmucosal delivery of cannabinoids

A - Human Necessities

61

K

A61K 31/352 (2006.01) A61K 9/00 (2006.01) A61K 9/70 (2006.01) A61M 37/00 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2487882

A method of transmucosally delivering a cannabinoid to a subject in need of such treatment comprising the steps of: administering to the subject a transmucosal preparation containing the cannabinoid wherein said transmucosal preparation is made by incorporating an effective amount of the cannabinoid via hot-melt extrusion technology, hot-melt molding, admixing or a solvent cast technique into a film matrix or a reservoir containing the cannabinoid, and attaching said transmucosal preparation to the mucosa of the subject.

L'invention concerne une méthode d'administration par voie transmuqueuse d'un cannabinoïde à un patient nécessitant un tel traitement, consistant à administrer au patient une préparation transmuqueuse contenant le cannabinoïde ou un réservoir contenant le cannabinoïde, et à fixer ladite préparation transmuqueuse à la muqueuse du patient. La préparation est fabriquée selon une technique consistant à incorporer une dose efficace du cannabinoïde dans un système matriciel, par extrusion à chaud, par moulage à chaud, par mélange ou par moulage par trempage en solution.

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