Transmucosal delivery of peptide derivatives

Details Transmucosal delivery of peptide derivatives Transmucosal delivery of peptide derivatives

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 7/56 (2006.01) C07K 14/505 (2006.01)

Patent

CA 2611836

What is described is a biological agent, comprised of a biologically active protein, or a fragment or a mimetic thereof, conjugated to at least one poly(alkylene oxide) chain having a size less than about 20 kDa, pharmaceutical formulations for intranasal delivery of said biological agent, or uses of said biological agent in the manufacture of said pharmaceutical formulation for administering said biological agent to a mammal.

La présente invention a trait à un agent biologique, comportant une protéine biologiquement active, ou un fragment ou un agent mimétique de celle-ci, conjuguée à au moins une chaîne poly(oxyde d'alkylène) ayant une taille inférieure à environ 20 kDa, des préparations pharmaceutiques pour l'administration intranasale dudit agent biologique, ou les utilisations dudit agent biologique dans la fabrication de ladite préparation pharmaceutique pour l'administration dudit agent biologique à un mammifère.

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