Transmucosal delivery system

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/70 (2006.01) A61K 31/727 (2006.01) A61M 37/00 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2190778

A device for delivering a heparinic anticoagulant across a mucosal surface in order to achieve or maintain a therapeutically effective blood level of the heparinic anticoagulant. The device involves a matrix containing a therapeutically effective amount of a heparinic anticoagulant, and a mucoadhesive or other mechanism for maintaining the matrix in contact with the mucosal surface for a time sufficient to allow release of the heparinic anticoagulant to the mucosal surface.

L'invention concerne un dispositif permettant l'administration d'un anticoagulant héparinique à travers une surface de muqueuse afin d'obtenir ou de maintenir un taux sanguin thérapeutiquement efficace dudit anticoagulant. Le dispositif est constitué d'une matrice contenant une dose thérapeutiquement efficace d'un anticoagulant héparinique, et d'un adhésif adhérant à la muqueuse ou d'un autre mécanisme destiné à maintenir la matrice en contact avec la surface de la muqueuse pendant un temps suffisant pour permettre la libération de l'anticoagulant héparinique sur la surface de muqueuse.

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