Transparent liquid for encapsulated drug delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/44 (2006.01) A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 38/11 (2006.01) A61K 38/12 (2006.01) A61K 38/23 (2006.01) A61K 38/36 (2006.01)

Patent

CA 2176927

There is provided a stable transparent multi-component composition useful for the delivery of water soluble active agents to animals. The compositions are formulated with a mixture of an oil phase, an aqueous phase, and a surfactant system along with the active agent to be delivered to the animal. The compositions are specially formulated to be compatible with capsules such as gelatin and starch capsules. The aqueous phase of tile compositions contains a substantial amount of polyethylene glycol and can optionally also contain a plasticizer. Preferred active agents are proteinaceous materials.

Composition transparente et stable à plusieurs constituants utilisable dans l'administration aux animaux d'agents actifs hydrosolubles. De telles compositions renferment un mélange d'une phase huileuse, d'une phase aqueuse et d'un système tensioactif, ainsi que l'agent actif à administrer à l'animal. Ces compositions sont spécialement formulées pour être compatibles avec les capsules telles que les capsules en gélatine et en amidon. La phase aqueuse de ces compositions renferme une quantité sensible de polyéthylène-glycol et éventuellement un plastifiant. Les agents actifs préférés sont les matières protéiniques.

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