Transparent polymer support for organic synthesis

B - Operations – Transporting – 01 – L

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B01L 3/00 (2006.01) C07K 1/04 (2006.01) C12M 1/00 (2006.01) C12M 1/22 (2006.01) C12M 1/24 (2006.01) C12M 1/34 (2006.01) C12M 1/36 (2006.01)

Patent

CA 2442998

The invention provides polyol (allyl carbonate) polymer solid supports. The supports can be modified for attachment of a chemical moiety or ligand. A solid support comprising one or more ligands immobilized to a polyol (allyl carbonate) polymer solid support. The solid support can be in the form of a bead, fiber, flat surface, microfluidic device, molded device, machined device, container, multi-well container such as a multi-well plate, and mass spectrometry sample holder. The solid supports can be used for a variety of applications, including chemical storage, chemical synthesis, combinatorial library synthesis, analytical devices, diagnostic devices, and tissue culture applications. The invention also provides methods of using the polyol (allyl carbonate) polymer solid supports.

L'invention concerne des supports solides en polymère polyol (carbonate d'allyle). On peut modifier lesdits supports par fixation d'un groupe fonctionnel ou d'un ligand. Un support solide contient un ou plusieurs ligand(s) fixé(s) à un support solide en polymère polyol (carbonate d'allyle). Ce support solide peut se présenter sous forme de perle, de fibre, de surface plane, de dispositif microfluide, de dispositif moulé, de dispositif usiné, de conteneur, conteneur à cuves multiples comme une plaque à cuves multiples et un porte-échantillons de spectrométrie de masse. Les supports solides peuvent servir à diverses applications, comprenant le stockage chimique, la synthèse chimique, la synthèse de bibliothèque combinatoire, les appareils d'analyse, les appareils de diagnostic et les applications de culture de tissus. L'invention concerne également des procédés d'utilisation des supports solides en polymère polyol (carbonate d'allyle).

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