Transplant acceptance inducing cells of monocytic origin and...

Details Transplant acceptance inducing cells of monocytic origin and... Transplant acceptance inducing cells of monocytic origin and...

C - Chemistry, Metallurgy

12

N

C12N 5/12 (2006.01) A61K 35/14 (2006.01) A61P 37/06 (2006.01) C07K 16/28 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2492383

The invention relates to transplant acceptance inducing cells of monocytic origin, their production as well as their use for generating transplant acceptance. The invention also relates to the monoclonal antibody GM-7, which specifically recognises human transplant acceptance inducing cells of the invention. The invention further relates to the use of the antibody GM-7 for detection and/or selection transplant-acceptance inducing cells.

L'invention concerne des cellules d'induction de l'acceptance d'un transplant d'origine monocytique, leur production, ainsi que leur utilisation dans la génération de l'acceptance d'un transplant. Cette invention a également trait à l'anticorps monoclonal GM-7 qui reconnaît spécifiquement des cellules d'induction de l'acceptance d'un transplant humain. Ladite invention a aussi pour objet l'utilisation de l'anticorps GM-7 dans la détection et/ou la sélection de cellules d'induction de l'acceptance d'un transplant.

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