Transport peptides derived from erns protein, cytotoxic...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/40 (2006.01) A61K 39/12 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2414308

The invention relates to peptides derived from or similar to the Erns~ protein of pestiviruses for type -specific diagnosis of infection, for eliciting antibiotic activity and for transport of substances into a cell. For among others these purposes the invention provides an isolated, synthetic or recombinant protein module or functional equivalent thereof comprising an amino acid sequence that is at least 75 % identical to an amino acid sequence of a peptide located from at about amino acid position 194 to 220 in a pestiviral Erns~ protein.

L'invention concerne des peptides dérivés de la protéine E<rns> de pestivirus -ou semblables à celle-ci- destinés au diagnostic spécifique de types d'infection, aux fins de production d'une activité antibiotique et de transport de substances dans une cellule. L'invention a pour but, entre autres, de décrire un module protéique recombiné ou de synthèse, isolé, ou un équivalent fonctionnel de celui-ci, comprenant une séquence d'acides aminés qui est à au moins 75 % identique à une séquence d'acides aminés d'un peptide situé environ à partir de la position d'acides aminés située entre 194 et 220 dans une protéine E<rns> pestivirale.

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