Transverse flow diagnostic device

G - Physics – 01 – N

Patent

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Details

167/37, 150/9

G01N 33/53 (2006.01) C12M 1/16 (2006.01) G01N 33/52 (2006.01) G01N 33/543 (2006.01) G01N 33/549 (2006.01) G01N 33/569 (2006.01) G01N 37/00 (2006.01)

Patent

CA 1269929

ABSTRACT OF THE DISCLOSURE This invention relates to a device for testing a specimen comprising a liquid input means having a receiving inlet and a discharge aperture, filter means positioned below the input means having at least one reaction zone for receiving liquid from the input means and at least one peripheral zone associated with the at least one reaction zone, absorbent means associated with only the peripheral zone of the filter means, and retainer means for holding the filter means in position below the liquid input means such that the at least one reaction zone receives liquid therefrom. It also relates to an improved diagnostic device for analyte assay which has a cylindrical body portion and a removably attached cap. The cap has a liquid inlet extending into the cylindrical body portion and has a conical shaped portion leading to a liquid discharge aperture formed therein. A pre-filter may be formed either in the liquid inlet or in a pre-filter container which can be used with the device. The pre- filter container has a substantially cylindrical body which conforms to and can be inserted in the liquid inlet forming part of the removable cap. The container has an open upper end and an associated removable closure, a bottom end sealed with a frangible material and, if desired, a pre-filter positioned in the container between the upper and lower ends. When liquid is placed in the container, the container may be inserted in the liquid inlet and a puncture device associ- ated with the liquid inlet ruptures the frangible material sealing the lower end and allows the liquid to be funneled to a reaction zone on a filter placed beneath or below the discharge aperture. Various size discharge apertures can be formed in the removable caps thereby allowing a particular cap to be associated with a device for a particular test.

510307

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