A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/19 (2006.01) A61K 31/16 (2006.01) A61K 31/167 (2006.01) A61K 31/18 (2006.01) A61K 31/197 (2006.01) A61K 31/198 (2006.01) A61K 31/22 (2006.01) A61K 31/222 (2006.01) A61K 31/255 (2006.01) A61K 31/27 (2006.01) A61K 31/575 (2006.01) A61K 31/616 (2006.01) A61P 25/00 (2006.01) A61P 25/06 (2006.01) A61P 25/08 (2006.01) A61P 25/14 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 25/30 (2006.01)
Patent
CA 2366038
Preparations and extracts of valerian, as well as isovaleramide, isovaleric acid, and certain structurally related compounds exhibit clinically significant pharmacological properties which implicate a treatment for a variety of pathological conditions, including spasticity and convulsions, which are ameliorated by effecting a modulation of CNS activity. The compositions in question generally are non-cytotoxic and do not elicit weakness or sedative activity at doses that are effective for the symptomatic treatment of such pathological conditions.
Les préparations et les extraits de valériane, ainsi que l'isovaléramide, l'acide isovalérique et certains composés structurellement apparentés présentent des propriétés pharmacologiques significatives d'un point de vue clinique qui conviennent au traitement de divers états pathologiques, notamment de la spasticité et des convulsions, états qui sont soulagés par une modulation de l'activité du système nerveux central. Les compositions en question sont, d'une manière générale, non cytotoxiques, ne suscitent pas de faiblesse ni n'ont d'activité sédative à des doses qui demeurent efficaces s'agissant du traitement symptomatique des états pathologiques susmentionnés.
Artman Linda D.
Balandrin Manuel
Smith Robert L.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Nps Pharmaceuticals Inc.
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