Treating avian influenza infections

A - Human Necessities – 61 – K

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A61K 38/21 (2006.01) A61K 31/13 (2006.01) A61K 31/221 (2006.01) A61K 31/351 (2006.01) A61K 31/7056 (2006.01) A61K 31/713 (2006.01) A61P 31/16 (2006.01)

Patent

CA 2525202

Avian influenza is treated with natural human alpha interferon, neuraminidase inhibitor(s) and ribavirin. Effects of influenza virus are mitigated with a dsRNA in combination with a neuraminidase influenza virus inhibitor. These two products, dsRNA, and alpha interferon, have therapeutic utility either given preventively (prophylactically) or in treatment of active disease. These unique immunological/antiviral actions, operating through immunological "cascades" ameliorates the lethal effects of viral mutation which, by causing resistance to commonly available drugs, greatly accelerates the death rate. For example, in 1918-1920, Avian Influenza caused the death of approximately 40 million people worldwide (ref. National Geographic, Sept. 2005).

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