C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/12 (2006.01) A61K 35/12 (2006.01) A61K 38/08 (2006.01) A61K 38/45 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2612146
The present invention provides a peptide comprising an amino acid sequence that is part of the amino acid sequence of CDK4 protein, or homologous to part of the amino acid sequence of CDK4 protein, which peptide is cytotoxic to, and/or inhibiting to the growth of, a cancer cell and/or stimulating to the growth of a non-cancerous cell and/or a control cell. Methods of identifying such peptides and medical uses of such peptides are also disclosed.
La présente invention a trait à un peptide comportant une séquence d'acides aminés formant partie de la séquence d'acides aminés de la protéine CDK4, ou homologue à une partie de la séquence d'acides aminés de la protéine CDK4, ledit peptide étant cytotoxique vis-à-vis, et ou inhibiteur de la croissance, d'une cellule cancéreuse et/ou stimulateur de la croissance d'une cellule non cancéreuse et/ou d'une cellule de contrôle. L'invention a également trait à de tels peptides et aux utilisations médicales de tels peptides.
Essex Jonathan
Kilburn Jeremy
Warenius Hilmar Meek
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Theryte Limited
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