Treating cancer

Details Treating cancer Treating cancer

G - Physics

01

N

G01N 33/574 (2006.01) A61K 31/00 (2006.01) A61K 31/337 (2006.01) A61K 33/24 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/32 (2006.01) C12N 15/09 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/00 (2006.01) G01N 33/15 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2321480

Provided is a method for measuring the radiosensivity of cells, which method comprises testing a sample comprising cells or an extract therefrom for: (a) the level of expression of p21, or for the abundance of p21 protein; and (b) the level of expression of Raf-1, or for the abundance of Raf-1 protein. The invention also provides a kit for measuring the radiosensitivity of cells, which kit comprises: (i) a means for testing for the level of expression of Raf-1 or for the abundance of Raf-1 protein; and (ii) a means for testing for the level of expression of p21 or for the abundance of p21 protein.

L'invention concerne un procédé de mesure de la radiosensibilité des cellules, ce procédé consistant à analyser un échantillon comprenant des cellules ou un extrait cellulaire afin de mesurer: (a) le niveau d'expression de p21 ou l'abondance de protéines p21; et (b) le niveau d'expression de Raf-1 ou l'abondance de protéines Raf-1. L'invention concerne également un ensemble permettant de mesurer la radiosensibilité des cellules, cet ensemble comprenant: (i) des moyens de mesure du niveau d'expression de Raf-1 ou de l'abondance de protéines Raf-1; et (ii) de moyens de mesure du niveau d'expression de p21 ou l'abondance de protéines p21.

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