Treating muscle wasting with selective androgen receptor...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/32 (2006.01) A61K 31/00 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/167 (2006.01)

Patent

CA 2469340

This invention provides: a method of treating a subject suffering from a muscle wasting disorder; a method of preventing a muscle wasting disorder in a subject; a method of treating, preventing, suppressing, inhibiting or reducing muscle loss in a subject suffering from a muscle wasting disorder; a method of treating, preventing, inhibiting, reducing or suppressing muscle wasting in a subject suffering from a muscle wasting disorder; and/or a method of treating, preventing, inhibiting, reducing or suppressing muscle protein catabolism in a subject suffering from a muscle wasting disorder, by administering to the subject a selective androgen receptor modulator (SARM) and/or its analog, derivative isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide or any combination thereof, as described herein.

La présente invention concerne: une méthode de traitement d'un sujet atteint d'amyotrophie; une méthode de prévention de l'amyotrophie chez un sujet; une méthode de traitement, de prévention, de suppression, d'inhibition ou de diminution de la perte musculaire chez un sujet atteint d'amyotrophie; une méthode de traitement, de prévention, d'inhibition, de diminution ou de suppression de l'amyotrophie chez un sujet atteint d'amyotrophie ; et/ou une méthode de traitement, de prévention, d'inhibition, de diminution ou de suppression du catabolisme de protéines musculaires chez un sujet atteint d'amyotrophie, par administration audit sujet d'un modulateur sélectif du récepteur d'androgène et/ou de son analogue, de son dérivé, de son isomère, de son métabolite, de son sel pharmaceutiquement acceptable, de son produit pharmaceutique, de son hydrate, de son N-oxyde ou de n'importe quelle combinaison, tel que décrit dans la présente invention.

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