Treating neurodegenerative diseases with progranulin (pgrn)

Details Treating neurodegenerative diseases with progranulin (pgrn) Treating neurodegenerative diseases with progranulin (pgrn)

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 45/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2712276

The invention relates to methods and compositions for treating a neurodegenerative disease. More particularly, the present invention is directed to methods of treatment of neurodegenerative diseases using progranulin and progranulin polypeptides, and methods of treatment of neurodegenerative diseases using effectors, or combinations of effectors, that modify progranulin expression.

L'invention porte sur des procédés et des compositions pour traiter une maladie neurodégénérative. Plus particulièrement, la présente invention porte sur des procédés de traitement de maladies neurodégénératives à l'aide de la progranuline et de polypeptides de progranuline, et sur des procédés de traitement de maladies neurodégénératives à l'aide d'effecteurs, ou de combinaisons d'effecteurs, qui modifient l'expression de la progranuline.

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