A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 8/40 (2006.01) A61Q 19/08 (2006.01)
Patent
CA 2379682
Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.
L'invention concerne de nouvelles méthodes et de nouvelles compositions pour le traitement de la peau vieillie et abîmée par l'environnement. Ces procédés et compositions améliorent l'aspect, la fonction, et les caractéristiques cliniques/biophysiques de la peau par l'activation d'au moins un enzyme protéolytique dans la couche cornée de la peau. Le traitement comprend l'application topique d'une nouvelle composition cosmétique combinant un tensioactif cationique tel que l'oxyde de N,N,-diméthyldodécyl amine (DMDAO), un tensioactif anionique tel que le dodécyl sulfate de sodium (SDS), ou le phosphate monoalkylique (MAP) et un chélateur tel que l'éthylène diamine tétraacétate (EDTA), afin de susciter une augmentation durable de la vitesse de remplacement de la couche cornée de l'épiderme au moyen d'une activation des protéases de la couche cornée. Cette stimulation durable de faible intensité a pour effet d'induire la réparation et le remplacement de la couche cornée, de l'épiderme et du derme de la peau, ainsi que des améliorations de l'aspect, de la fonction et des capacités anti-vieillissement de la peau.
Schiltz John R.
Goudreau Gage Dubuc
Mary Kay Inc.
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