G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07G 3/00 (2006.01) C07H 1/06 (2006.01) C07K 16/18 (2006.01)
Patent
CA 2355096
Inositolphosphoglycans (IPGs), and in particular A-type substances comprising myo-inositol, are tumour autocrine factors (TAFs), that is factors which cause tumour cell proliferation. The use of A-type IPG antagonists for the treatment of cancer and a method for the diagnosis or prognosis of cancer based on the presence or amount of IPGs in a sample from a patient is disclosed.
Les inositolphosphoglycanes (IPG) et, en particulier, les substances de type A contenant myo-inositol, sont des facteurs autocrine de tumeurs (TAF), c'est-à-dire des facteurs qui provoquent la prolifération cellulaire tumorale. L'invention concerne l'utilisation d'antagonistes IPG de type A pour le traitement du cancer, et une méthode de diagnostic ou de pronostic d'un cancer fondée sur la présence ou la quantité d'IPG dans un prélèvement effectué chez un patient.
Caro Hugo
Rademacher Thomas William
Bereskin & Parr
Rademacher Group Limited
Rodaris Pharmaceuticals Limited
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