Treatment and diagnostic methods for fibrosis related disorders

G - Physics – 01 – N

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G01N 33/68 (2006.01) A61K 38/17 (2006.01) A61K 38/39 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2692637

Compositions and methods are provided for the treatment of fibrosis related disorders utilizing the ratio of the con-centration of serum amyloid P (SAP) to C-reactive protein (CRP) in a patient. The methods may further comprise determining the R1 31/H1 31 polymorphism of Fc.gamma.RIIA. Diagnostic methods are also provided.

La présente invention concerne des compositions et des procédés prévus pour le traitement des troubles liés aux fibroses utilisant le rapport de concentration d'amyloïde de sérum P (SAP) sur protéine réactive C (CRP) chez un patient. Les procédés peuvent aussi comprendre la détermination du polymorphisme Rl 31/Hl 31 de Fc?RIIA. L'invention concerne également des procédés de diagnostic.

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