Treatment and prevention of neurodegenerative diseases using...

A - Human Necessities – 61 – K

Patent

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A61K 48/00 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2677273

Provided herein are compositions and methods for treating and/or preventing neurodegenerative disease, such as Alzheimer's disease. In particular aspects, compositions administered herein encode a cellular immune response element. The compositions may be prepared and administered in such a manner that the cellular immune response element coding sequence is expressed in the subject to which the composition is administered. The compositions include expression systems, delivery systems, and certain cellular immune response element genes.

L'invention propose des compositions et des procédés destinés au traitement et/ou à la prévention d'une maladie neurodégénérative, telle que la maladie d'Alzheimer. Sous des aspects particuliers, les compositions administrées codent un élément de réponse immunitaire cellulaire. Les compositions peuvent être préparées et administrées de manière à ce que la séquence codant l'élément de réponse immunitaire cellulaire soit exprimée chez le sujet auquel la composition est administrée. Les compositions comprennent des systèmes d'expression, des systèmes d'administration et certains gènes d'élément de réponse immunitaire cellulaires.

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