A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) C07K 16/28 (2006.01) C12N 9/10 (2006.01)
Patent
CA 2680854
The present invention relates to the treatment of EGFR-mediated disease, particularly cancer by inhibiting or blocking EGFR and src in combination or simultaneously. The invention relates to treatment, prevention, or modulation of cancer, particularly EGFR- mediated disease, with one or more EGFR modulator and src inhibitor in combination. The invention further relates to the treatment of cancer with anti-EGFR antibodies and src inhibitors. Methods and compositions for treatment of cancer with the antibody anti- EGFR mAb806 in combination or series with a src inhibitor or src inhibitors are described.
L'invention concerne le traitement d'une maladie favorisée par l'EGFR, en particulier le cancer, par inhibition ou blocage d'EGFR et de src en combinaison, ou simultanément. L'invention concerne le traitement, la prévention, ou la modulation du cancer, en particulier une maladie favorisée par l'EGFR, avec un ou plusieurs modulateurs d'EGFR et inhibiteurs de src en combinaison. L'invention concerne en outre le traitement du cancer avec des anticorps anti-EGFR, et des inhibiteurs de src. Des procédés et compositions pour le traitement du cancer avec l'anticorps anti-EGFR mAb806 en association ou en séries avec un inhibiteur de src ou des inhibiteurs de src sont décrits.
Cavenee Webster
Furnari Frank
Johns Terrance Grant
Scott Andrew
Ludwig Institute For Cancer Research
Torys Llp
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