A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) A61K 31/495 (2006.01) A61K 31/704 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2367240
The present invention relates to a method and a medicament for pharmacological treatment of accidental extravasation of topoisomerase II poisons such as anthracyclines. In particular, the invention relates to the use of a topo II catalytic inhibitor such as the bisdioxopiperazine ICRF-187 for the manufacture of a medicament for the treatment of an accidental extravasation of a topoisomerase II poison and a method for treatment of such extravasation of a topoisomerase poison such as the anthracyclines daunorubicin, doxorubicin, epirubicin, or idarubicin. In addition, the invention relates to a kit for such treatment.
La présente invention concerne un procédé et un médicament destinés au traitement pharmacologique d'un épanchement accidentel de topoisomérase II toxique telle que les anthracyclines. L'invention concerne en particulier l'utilisation d'un inhibiteur catalytique de topo II tel que la bisdioxopipérazine ICRF-187 pour la production d'un médicament destiné au traitement d'un épanchement accidentel de topoisomérase II toxique et un procédé de traitement d'un tel épanchement d'une topoisomérase toxique telle que les anthracyclines - la daunorubicine, la doxorubicine, d'épirubicine ou l'idarubicine. En plus, l'invention concerne un kit d'un tel traitement.
Jensen Peter Buhl
Langer Seppo W.
Sehested Maxwell
Antianthra Aps
Sim & Mcburney
Topotarget A/s
LandOfFree
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