Treatment of age-related memory impairment using...

Details Treatment of age-related memory impairment using... Treatment of age-related memory impairment using...

A - Human Necessities

61

K

A61K 31/661 (2006.01) A61K 9/127 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2572982

Symptoms, including biochemical correlates, of age-related memory loss (ARML) in a mammal are beneficially affected by administering to the mammal small doses of bodies, such as liposomes, of a size resembling that of mammalian cells, the bodies having phosphate glycerol head groups presented exteriorly on their surfaces. Preferred are liposomes comprised of 50-100% phosphatidylglycerol, with the phosphoglycerol headgroups thereof exteriorly presented.

Les symptômes, dont les corrélats biochimiques, des altérations de la mémoire liées à l'âge (ARML) chez un mammifère sont avantageusement soignés par administration audit mammifère de petites doses de corps, tels que les liposomes, de taille analogue à celle de cellules mammifères, lesdits corps comprenant des têtes polaires phosphate-glycérol présentées à l'extérieur, à leurs surfaces. Des liposomes préférés comprennent 50 à 100 % en poids de phosphatidylglycérol, leurs têtes polaires phosphoglycérol étant présentées à l'extérieur.

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