Treatment of alzheimer's disease employing inhibitors of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 277/36 (2006.01) A61K 31/395 (2006.01) C07D 277/20 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01)

Patent

CA 2144385

This invention provides novel benzylidene rhodanines which are useful as agents in treating or preventing conditions associated with .beta.-amyloid peptide. This invention further provides methods of treating or preventing Alzheimer's Disease which comprises administering to a mammal in need thereof an effective amount of one or more of the benzylidene rhodanines of the present invention. This invention also provides methods for reducing blood glucose concentrations which comprises administering to a mammal in need thereof an effective amount of one or more of the benzylidene rhodanines of the present invention.

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