Treatment of amyotrophic lateral sclerosis with...

A - Human Necessities – 61 – K

Patent

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A61K 31/565 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2600064

Methods for modulating hormonal pathways involving the progesterone receptor in a subject with a neurodegenerative disorder, are provided. Progesterone receptor activity is modulated by administering an effective amount of an progesterone receptor modulating pharmacological agent to a subject such that the progesterone receptor modulating pharmacological agent interacts with the progesterone receptor and alters the expression of a protein associated with the neurodegenerative disease.

L'invention concerne des méthodes permettant de moduler des canaux hormonaux impliquant le récepteur de la progestérone chez un sujet souffrant d'un trouble neurodégénératif. L'activité du récepteur de la progestérone est modulée par administration d'une quantité efficace d'agent pharmacologique modulant le récepteur de la progestérone à un sujet de sorte que cet agent interagit avec ledit récepteur de la progestérone et modifie l'expression d'une protéine associée à la maladie neurodégénérative.

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