Treatment of an intestinal adenoma and/or adenocarcinoma by...

Details Treatment of an intestinal adenoma and/or adenocarcinoma by... Treatment of an intestinal adenoma and/or adenocarcinoma by...

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 38/55 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2586781

The invention relates to the field of biochemistry and medicine. More specifically the invention relates to methods and pharmaceuticals for the treatment of intestinal neoplasia. The invention discloses the surprising finding that inhibitors of Notch pathway activation (for example g-secretase inhibitors) are extremely useful in the treatment of intestinal adenoma and/or adenocarcinoma

La présente invention est liée aux domaines de la biochimie et de la médecine. La présente invention décrit plus spécifiquement des méthodes et des médicaments pour le traitement de la néoplasie intestinale. La présente invention décrit des découvertes surprenantes selon lesquelles des inhibiteurs de l~activation de la voie Notch (par exemple les inhibiteurs de g-secrétase) sont particulièrement utiles dans le traitement d~un adénome et/ou d~un adénocarcinome intestinal.

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