Treatment of antibiotic associated diarrhea

Details Treatment of antibiotic associated diarrhea Treatment of antibiotic associated diarrhea

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 1/22 (2006.01) C07K 14/33 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2181359

This invention relates to treatment of antibiotic associated diarrhea, including Clostridium difficile associated diarrhea (CDAD) and pseudomembranous colitis (PMC), using oligosaccharide compositions which bind C. difficile toxin A. More specifically, the invention concerns neutralization of C. difficile toxin A associated with CDAD.

L'invention se rapporte au traitement de la diarrhée associée à la prise d'antibiotiques, notamment la diarrhée associée à Clostridium difficile (CDAD) et la colite pseudomembraneuse (PMC), consistant à utiliser des compositions à base d'oligosaccharides qui fixent la toxine A de C. difficile. L'invention concerne plus particulièrement la neutralisation de la toxine A de C. difficile associée à la diarrhée due à C. difficile.

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