Treatment of arthritis with mek inhibitors

Details Treatment of arthritis with mek inhibitors Treatment of arthritis with mek inhibitors

C - Chemistry, Metallurgy

07

D

C07D 333/02 (2006.01) A61K 31/00 (2006.01) A61K 31/136 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) A61K 31/192 (2006.01) A61K 31/195 (2006.01) A61K 31/341 (2006.01) A61K 31/351 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/4406 (2006.01) A61K 31/4409 (2006.01) A61K 31/445 (2006.01) A61K 31/4453 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61K 31/63 (2006.01) A61P 19/02 (2006.01) A61P 29/

Patent

CA 2346448

This invention provides a method for preventing and treating arthritis in a mammal suffering from arthritis and in need of treatment, or suspected of developing arthritis, said method comprising the step of administering an effective antiarthritic amount of a MEK inhibitor, including a compound of Formula (I) and Formula (II).

L'invention se rapporte à un procédé de prévention et de traitement de l'arthrite chez un mammifère souffrant d'arthrite et nécessitant un traitement, ou supposé enclin à souffrir d'arthrite. Ledit procédé consiste à administrer une quantité anti-arthritique efficace d'un inhibiteur de la kinase MEK, et notamment un composé représenté par la formule (I) et la formule (II).

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