C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2733432
The present invention provides novel methods of treatment of multiple sclerosis and other autoimmune diseases or inflammatory disorders, and antagonists, including isolated binding proteins for use in the novel methods. There is provided a method of treating multiple sclerosis comprising the neutralization of the biological activity of IL-7 by binding to CD127 or IL-7. The isolated binding proteins may also neutralize the biological activity of TSLP.
La présente invention concerne de nouveaux procédés de traitement de la sclérose en plaques et dautres maladies auto-immunes ou troubles inflammatoires, et des antagonistes, comprenant des protéines de liaison isolées pour une utilisation dans les nouveaux procédés. La présente invention concerne en outre un procédé de traitement de la sclérose en plaques comprenant la neutralisation de lactivité biologique de IL-7 par liaison à CD127 ou IL-7. Les protéines de liaison isolées peuvent également neutraliser lactivité biologique de TSLP.
Leung Stewart
Li Lixin
Liu Xuebin
Lu Hongtao
Tsui Ping
Glaxo Group Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Treatment of autoimmune and inflammatory disease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of autoimmune and inflammatory disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of autoimmune and inflammatory disease will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1436750