Treatment of autoimmune, proliferative and inflammatory...

A - Human Necessities – 61 – K

Patent

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A61K 31/74 (2006.01)

Patent

CA 2406013

Compositions comprising non-ionic block copolymers are useful for the treatment of autoimmune, inflammatory and proliferative diseases and for reducing graft/implantation rejection. The present invention also relates to methods of treating animals having various autoimmune, inflammatory and proliferative diseases. The present invention also relates to methods of reducing inflammation in an animal comprising administering the compositions of the invention. Also, the present invention relates to methods of reducing autoimmune responses and to methods of reducing graft/implantation rejection comprising administering the compositions of the inventions. A typical embodiment is a mixture of Pluronics F127 and L61.

L'invention concerne des compositions comprenant des copolymères bloc non ioniques destinées au traitement de maladies auto-immunes, inflammatoires et prolifératives et à la réduction des rejets de greffe/implantation. La présente invention concerne également des méthodes de traitement destinées aux animaux atteints de différentes maladies auto-immunes, inflammatoires et prolifératives. La présente invention concerne également des méthodes de réduction d'inflammations chez un animal, comprenant l'administration de ces compositions. La présente invention concerne également des méthodes permettant de réduire la réponse auto-immune et des méthodes permettant de réduire le rejet de greffe/implantation, comprenant l'administration de ces compositions. Un mode de réalisation caractéristique de l'invention concerne un mélange de Pluronic F127 et L61.

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