A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/40 (2006.01) A61K 35/74 (2006.01) A61K 38/46 (2006.01) A61K 47/48 (2006.01) C07K 16/12 (2006.01) C12Q 1/02 (2006.01) C12Q 1/18 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2176237
The lipopolysaccharide of bacteria associated with chronic inflammatory diseases is unable to induce expression of leukocyte adhesion molecules, or selectins, on endothelial cells, and is also capable of inhibiting the induction of selectin expression by bacteria normally associated with acute endotoxin disease. New approaches to treatment of these diseases, and the diagnosis of susceptibility to chronic baterial-associated inflammatory diseases, are provided.
Le lipopolysaccharide des bactéries associées aux affections inflammatoires chroniques ne peut pas induire l'expression des molécules d'adhérence leucocytaire, ou sélectines, sur les cellules endothéliales, et il peut inhiber l'induction de l'expression des sélectines par les bactéries normalement associées aux affections aiguës dues aux endotoxines. De nouvelles approches du traitement de ces maladies sont décrites, ainsi que le diagnostic de la sensibilité aux affections inflammatoires chroniques d'origine bactérienne.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
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