Treatment of brain derived neurotrophic factor (bdnf)...

Details Treatment of brain derived neurotrophic factor (bdnf)... Treatment of brain derived neurotrophic factor (bdnf)...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 38/16 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2752237

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Brain derived neurotrophic factor (BDNF), in particular, by targeting natural antisense polynucleotides of Brain derived neurotrophic factor (BDNF). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of BDNF.

La présente invention concerne des oligonucléotides antisens qui modulent l'expression et/ou la fonction du facteur neurotrophique dérivé du cerveau (BDNF), en particulier en ciblant les polynucléotides antisens naturels dudit facteur neurotrophique dérivé du cerveau (BDNF). L'invention porte également sur l'identification desdits oligonucléotides antisens et sur leur utilisation dans le cadre du traitement des maladies et troubles associés à l'expression du BDNF.

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