Treatment of c. difficile toxin b associated conditions

Details Treatment of c. difficile toxin b associated conditions Treatment of c. difficile toxin b associated conditions

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 31/7016 (2006.01) A61K 31/702 (2006.01) A61P 1/12 (2006.01)

Patent

CA 2321927

This invention relates to prevention and/or treatment of antibiotic associated diarrhea, including Clostridium difficile associated diarrhea (CDAD), pseudomembranous colitis (PMC) and other conditions associated with C. difficile infection, using oligosaccharide compositions which bind C. difficile toxin B. More specifically, the invention concerns neutralization of C. difficile toxin B associated with such conditions.

L'invention concerne la prévention et/ou le traitement de la diarrhée consécutive à un traitement antibiotique, dont la diarrhée associée à Clostridium difficile, la colite pseudo-membraneuse et d'autres états associés à l'infection à C. difficile, au moyen de compositions à base d'oligosaccharides, qui fixent la toxine B de C. difficile. L'invention porte, plus spécifiquement, sur la neutralisation de la toxine B de C. difficile associée à ces états.

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