Treatment of c. difficile toxin b associated conditions

Details Treatment of c. difficile toxin b associated conditions Treatment of c. difficile toxin b associated conditions

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2388187

This invention relates to prevention and/or treatment of antibiotic associated diarrhea, including Clostridium difficile associated diarrhea (CDAD), pseudomembranous colitis (PMC) and other conditions associated with C. difficile infection, using oligosaccharide compositions which bind C. difficile toxin B. More specifically, the invention concerns neutralization of C. difficile toxin B associated with such conditions.

La présente invention concerne la prévention et /ou le traitement de la diarrhée associée aux antibiotiques, notamment la diarrhée associée à Clostridium difficile (CDAD), la colite pseudo-membraneuse (PMC) et d'autres pathologies associées aux infections à C. difficile, par l'utilisation de compositions d'oligosaccharide qui se fixent sur la toxine B de C. difficile. La présente invention concerne plus spécifiquement la neutralisation de la toxine B de C. difficile associée à ces pathologies.

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