A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2388998
The present invention relates to a method for the treatment of tumours, the method comprising inhibiting angiogenesis in a subject in need thereof characterised in that angiogenesis is inhibited by administering to the subject an agent which inhibits induction of EGR, an agent which decreases expression of EGR or an agent which decreases the nuclear accumulation or activity of EGR. The present invention also relates to a method of screening for agents which inhibits angiogenesis.
La présente invention concerne un procédé permettant de traiter des tumeurs. Ce procédé consiste à inhiber l'angiogenèse chez un sujet qui le nécessite. Ce procédé est caractérisé en ce que l'angiogenèse est inhibée par administration, chez un sujet, d'un agent qui inhibe l'induction de la réponse de croissance précoce (EGR), d'un agent qui diminue l'expression de la réponse de croissance précoce ou d'un agent qui diminue l'accumulation ou l'activité nucléaire de la réponse de croissance précoce. La présente invention concerne également un procédé permettant de cribler des agents qui inhibent l'angiogenèse.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Unisearch Limited
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