Treatment of cancer by the use of anti fas antibody

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 31/282 (2006.01) A61K 31/337 (2006.01) A61K 31/4745 (2006.01) A61K 31/513 (2006.01) A61K 31/517 (2006.01) A61K 31/704 (2006.01) A61K 31/7088 (2006.01) A61K 33/24 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2511604

The present invention provides a method of killing cancer cells and method of treatment of cancer comprising administration of a therapeutically effective amount of a) a specific binding member which binds to a cell death receptor or a nucleic acid encoding said binding member and (b) a chemotherapeutic agent. The binding member pereferably binds to a Fas receptor. Also described are medicaments for use in treating cancer.

La présente invention concerne une méthode de neutralisation de cellules cancéreuses et une méthode de traitement du cancer, qui consistent à administrer une quantité thérapeutiquement efficace: a) d'un élément de liaison spécifique qui se lie à un récepteur de la mort cellulaire ou un acide nucléique codant ledit élément; et b) d'une substance chimiothérapeutique. L'élément de liaison se lie, de préférence, à un récepteur de Fas. L'invention concerne en outre des médicaments destinés au traitement du cancer.

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